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Metastatic Genitourinary System Carcinoma

MedGen UID:
1636800
Concept ID:
C4687546
Neoplastic Process
Synonyms: Metastatic Genitourinary Cancer; Metastatic Genitourinary Carcinoma; Metastatic Urogenital Carcinoma

Definition

A carcinoma that arises from the genitourinary system and has metastasized to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Genitourinary System Carcinoma

Professional guidelines

PubMed

Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Galsky MD, Hahn NM, Rosenberg J, Sonpavde G, Hutson T, Oh WK, Dreicer R, Vogelzang N, Sternberg CN, Bajorin DF, Bellmunt J
J Clin Oncol 2011 Jun 10;29(17):2432-8. Epub 2011 May 9 doi: 10.1200/JCO.2011.34.8433. PMID: 21555688

Recent clinical studies

Etiology

Rouprêt M, Seisen T, Birtle AJ, Capoun O, Compérat EM, Dominguez-Escrig JL, Gürses Andersson I, Liedberg F, Mariappan P, Hugh Mostafid A, Pradere B, van Rhijn BWG, Shariat SF, Rai BP, Soria F, Soukup V, Wood RG, Xylinas EN, Masson-Lecomte A, Gontero P
Eur Urol 2023 Jul;84(1):49-64. Epub 2023 Mar 24 doi: 10.1016/j.eururo.2023.03.013. PMID: 36967359
Mohanty SK, Lobo A, Cheng L
Hum Pathol 2023 Jun;136:123-143. Epub 2022 Sep 6 doi: 10.1016/j.humpath.2022.08.006. PMID: 36084769
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Shbair AT, Yasin AI, Topçu A, Coban G, Uzunoglu GD, Şimşek M
Int J Surg Pathol 2022 Jun;30(4):466-469. Epub 2021 Dec 27 doi: 10.1177/10668969211067923. PMID: 34955060
Mehta NJ, Torno R, Sorra T
South Med J 2000 Jul;93(7):713-5. PMID: 10923963

Diagnosis

Rouprêt M, Seisen T, Birtle AJ, Capoun O, Compérat EM, Dominguez-Escrig JL, Gürses Andersson I, Liedberg F, Mariappan P, Hugh Mostafid A, Pradere B, van Rhijn BWG, Shariat SF, Rai BP, Soria F, Soukup V, Wood RG, Xylinas EN, Masson-Lecomte A, Gontero P
Eur Urol 2023 Jul;84(1):49-64. Epub 2023 Mar 24 doi: 10.1016/j.eururo.2023.03.013. PMID: 36967359
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Michalski BM, Pfeifer JD, Mutch D, Council ML
Dermatol Surg 2021 Feb 1;47(2):174-183. doi: 10.1097/DSS.0000000000002584. PMID: 32947298
Gibb J, Babawale O, Phan YC, Karim O
BMJ Case Rep 2020 Nov 30;13(11) doi: 10.1136/bcr-2020-237115. PMID: 33257377Free PMC Article
Bellur S, Van der Kwast T, Mete O
Hum Pathol 2019 Mar;85:313-327. Epub 2018 Nov 24 doi: 10.1016/j.humpath.2018.11.016. PMID: 30481509

Therapy

Zlotta AR, Ballas LK, Niemierko A, Lajkosz K, Kuk C, Miranda G, Drumm M, Mari A, Thio E, Fleshner NE, Kulkarni GS, Jewett MAS, Bristow RG, Catton C, Berlin A, Sridhar SS, Schuckman A, Feldman AS, Wszolek M, Dahl DM, Lee RJ, Saylor PJ, Michaelson MD, Miyamoto DT, Zietman A, Shipley W, Chung P, Daneshmand S, Efstathiou JA
Lancet Oncol 2023 Jun;24(6):669-681. Epub 2023 May 12 doi: 10.1016/S1470-2045(23)00170-5. PMID: 37187202
Motzer RJ, Powles T, Burotto M, Escudier B, Bourlon MT, Shah AY, Suárez C, Hamzaj A, Porta C, Hocking CM, Kessler ER, Gurney H, Tomita Y, Bedke J, Zhang J, Simsek B, Scheffold C, Apolo AB, Choueiri TK
Lancet Oncol 2022 Jul;23(7):888-898. Epub 2022 Jun 7 doi: 10.1016/S1470-2045(22)00290-X. PMID: 35688173Free PMC Article
Rhea LP, Mendez-Marti S, Kim D, Aragon-Ching JB
Cancer Treat Res Commun 2021;26:100296. Epub 2020 Dec 24 doi: 10.1016/j.ctarc.2020.100296. PMID: 33421822
Michalski BM, Pfeifer JD, Mutch D, Council ML
Dermatol Surg 2021 Feb 1;47(2):174-183. doi: 10.1097/DSS.0000000000002584. PMID: 32947298
Davis ID, Martin AJ, Stockler MR, Begbie S, Chi KN, Chowdhury S, Coskinas X, Frydenberg M, Hague WE, Horvath LG, Joshua AM, Lawrence NJ, Marx G, McCaffrey J, McDermott R, McJannett M, North SA, Parnis F, Parulekar W, Pook DW, Reaume MN, Sandhu SK, Tan A, Tan TH, Thomson A, Tu E, Vera-Badillo F, Williams SG, Yip S, Zhang AY, Zielinski RR, Sweeney CJ; ENZAMET Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials Group
N Engl J Med 2019 Jul 11;381(2):121-131. Epub 2019 Jun 2 doi: 10.1056/NEJMoa1903835. PMID: 31157964

Prognosis

Rose TL, Kim WY
JAMA 2024 Sep 24;332(12):1001-1010. doi: 10.1001/jama.2024.12848. PMID: 39196544
Powles T, Park SH, Caserta C, Valderrama BP, Gurney H, Ullén A, Loriot Y, Sridhar SS, Sternberg CN, Bellmunt J, Aragon-Ching JB, Wang J, Huang B, Laliberte RJ, di Pietro A, Grivas P
J Clin Oncol 2023 Jul 1;41(19):3486-3492. Epub 2023 Apr 18 doi: 10.1200/JCO.22.01792. PMID: 37071838Free PMC Article
Motzer RJ, Powles T, Burotto M, Escudier B, Bourlon MT, Shah AY, Suárez C, Hamzaj A, Porta C, Hocking CM, Kessler ER, Gurney H, Tomita Y, Bedke J, Zhang J, Simsek B, Scheffold C, Apolo AB, Choueiri TK
Lancet Oncol 2022 Jul;23(7):888-898. Epub 2022 Jun 7 doi: 10.1016/S1470-2045(22)00290-X. PMID: 35688173Free PMC Article
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Mehta NJ, Torno R, Sorra T
South Med J 2000 Jul;93(7):713-5. PMID: 10923963

Clinical prediction guides

Rose TL, Kim WY
JAMA 2024 Sep 24;332(12):1001-1010. doi: 10.1001/jama.2024.12848. PMID: 39196544
Zlotta AR, Ballas LK, Niemierko A, Lajkosz K, Kuk C, Miranda G, Drumm M, Mari A, Thio E, Fleshner NE, Kulkarni GS, Jewett MAS, Bristow RG, Catton C, Berlin A, Sridhar SS, Schuckman A, Feldman AS, Wszolek M, Dahl DM, Lee RJ, Saylor PJ, Michaelson MD, Miyamoto DT, Zietman A, Shipley W, Chung P, Daneshmand S, Efstathiou JA
Lancet Oncol 2023 Jun;24(6):669-681. Epub 2023 May 12 doi: 10.1016/S1470-2045(23)00170-5. PMID: 37187202
Alchahin AM, Mei S, Tsea I, Hirz T, Kfoury Y, Dahl D, Wu CL, Subtelny AO, Wu S, Scadden DT, Shin JH, Saylor PJ, Sykes DB, Kharchenko PV, Baryawno N
Nat Commun 2022 Sep 30;13(1):5747. doi: 10.1038/s41467-022-33375-w. PMID: 36180422Free PMC Article
Gerlinger M, Rowan AJ, Horswell S, Math M, Larkin J, Endesfelder D, Gronroos E, Martinez P, Matthews N, Stewart A, Tarpey P, Varela I, Phillimore B, Begum S, McDonald NQ, Butler A, Jones D, Raine K, Latimer C, Santos CR, Nohadani M, Eklund AC, Spencer-Dene B, Clark G, Pickering L, Stamp G, Gore M, Szallasi Z, Downward J, Futreal PA, Swanton C
N Engl J Med 2012 Mar 8;366(10):883-892. doi: 10.1056/NEJMoa1113205. PMID: 22397650Free PMC Article
Hodzic J, Golka K, Schulze H
Med Sci Monit 2004 Aug;10(8):CS46-8. Epub 2004 Jul 23 PMID: 15278003

Recent systematic reviews

Zhu J, Lu Z, Cai X, Chen W
Int Wound J 2024 Jan;21(1):e14367. Epub 2023 Sep 14 doi: 10.1111/iwj.14367. PMID: 37706271Free PMC Article
Santandreu-Morales I, Redondo-Cerezo E, Martín-Enguix D
Med Clin (Barc) 2023 Mar 10;160(5):206-212. Epub 2022 Dec 14 doi: 10.1016/j.medcli.2022.11.001. PMID: 36526448
Crocerossa F, Autorino R, Derweesh I, Carbonara U, Cantiello F, Damiano R, Rubio-Briones J, Roupret M, Breda A, Volpe A, Mir MC; European Section of Urologic-Oncology (ESOU) of European Association of Urology (EAU)
Minerva Urol Nephrol 2023 Feb;75(1):1-16. Epub 2022 Sep 12 doi: 10.23736/S2724-6051.22.04881-9. PMID: 36094386
Tariq A, McCart Reed AE, Morton A, Porten S, Vela I, Williams ED, Yaxley JW, Black PC, Roberts MJ
Eur Urol Focus 2022 Sep;8(5):1256-1269. Epub 2021 Aug 21 doi: 10.1016/j.euf.2021.07.016. PMID: 34429271
Bizzarri N, Vellone VG, Parodi L, Calanni Fraccono L, Ghirardi V, Costantini S, Menada MV, Sala P
J Obstet Gynaecol 2017 Nov;37(8):975-981. Epub 2017 Jun 28 doi: 10.1080/01443615.2017.1318269. PMID: 28657384

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