U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Metastatic Bladder Plasmacytoid Urothelial Carcinoma

MedGen UID:
1682285
•Concept ID:
C4763829
•
Neoplastic Process
Synonyms: Metastatic Infiltrating Bladder Urothelial Carcinoma, Plasmacytoid Variant; Metastatic Invasive Bladder Urothelial Carcinoma, Plasmacytoid Variant; Metastatic Plasmacytoid Urothelial Carcinoma of the Bladder

Definition

Bladder plasmacytoid urothelial carcinoma that has spread to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Bladder Plasmacytoid Urothelial Carcinoma

Professional guidelines

PubMed

Metastatic Pleomorphic Lobular Carcinoma of the Breast to the Urinary Bladder: A Report of 10 Cases and Assessment of TRPS1 in the Differential Diagnosis With Plasmacytoid Urothelial Carcinoma.
Zhang GN, Susnik B, Paulsen EJ, Lyons LL, Delma KS, Jorda M, Epstein JI, Kryvenko ON
Arch Pathol Lab Med 2024 Oct 1;148(10):1110-1118. doi: 10.5858/arpa.2023-0379-OA. PMID: 38217332
What Is the Prognostic and Clinical Importance of Urothelial and Nonurothelial Histological Variants of Bladder Cancer in Predicting Oncological Outcomes in Patients with Muscle-invasive and Metastatic Bladder Cancer? A European Association of Urology Muscle Invasive and Metastatic Bladder Cancer Guidelines Panel Systematic Review.
Veskimäe E, Espinos EL, Bruins HM, Yuan Y, Sylvester R, Kamat AM, Shariat SF, Witjes JA, Compérat EM
Eur Urol Oncol 2019 Nov;2(6):625-642. Epub 2019 Oct 8 doi: 10.1016/j.euo.2019.09.003. PMID: 31601522

Recent clinical studies

Etiology

Adjuvant Chemotherapy and Survival After Radical Cystectomy in Histologic Subtype Bladder Cancer.
Koehne EL, Bakaloudi DR, Ghali F, Nyame Y, Schade GR, Grivas P, Yezefski TA, Hawley JE, Yu EY, Hsieh AC, Montgomery RB, Psutka SP, Gore JL, Wright JL
Clin Genitourin Cancer 2024 Jun;22(3):102100. Epub 2024 Apr 25 doi: 10.1016/j.clgc.2024.102100. PMID: 38763862
What Is the Prognostic and Clinical Importance of Urothelial and Nonurothelial Histological Variants of Bladder Cancer in Predicting Oncological Outcomes in Patients with Muscle-invasive and Metastatic Bladder Cancer? A European Association of Urology Muscle Invasive and Metastatic Bladder Cancer Guidelines Panel Systematic Review.
Veskimäe E, Espinos EL, Bruins HM, Yuan Y, Sylvester R, Kamat AM, Shariat SF, Witjes JA, Compérat EM
Eur Urol Oncol 2019 Nov;2(6):625-642. Epub 2019 Oct 8 doi: 10.1016/j.euo.2019.09.003. PMID: 31601522
Urothelial Carcinoma In Situ of the Bladder With Glandular Differentiation: Report of 92 Cases.
Yang Z, Epstein JI
Am J Surg Pathol 2018 Jul;42(7):971-976. doi: 10.1097/PAS.0000000000001073. PMID: 29683821
Plasmacytoid Urothelial Carcinoma of Ureter with Retroperitoneal Metastasis: A Case Report.
Jibril A, Stevens AC
Am J Case Rep 2018 Feb 13;19:158-162. doi: 10.12659/ajcr.906679. PMID: 29434183Free PMC Article
Plasmacytoid carcinoma of the bladder: a urothelial carcinoma variant with a predilection for intraperitoneal spread.
Ricardo-Gonzalez RR, Nguyen M, Gokden N, Sangoi AR, Presti JC Jr, McKenney JK
J Urol 2012 Mar;187(3):852-5. Epub 2012 Jan 15 doi: 10.1016/j.juro.2011.10.145. PMID: 22245324

Diagnosis

Metastatic Pleomorphic Lobular Carcinoma of the Breast to the Urinary Bladder: A Report of 10 Cases and Assessment of TRPS1 in the Differential Diagnosis With Plasmacytoid Urothelial Carcinoma.
Zhang GN, Susnik B, Paulsen EJ, Lyons LL, Delma KS, Jorda M, Epstein JI, Kryvenko ON
Arch Pathol Lab Med 2024 Oct 1;148(10):1110-1118. doi: 10.5858/arpa.2023-0379-OA. PMID: 38217332
Plasmacytoid Urothelial Carcinoma of Ureter with Retroperitoneal Metastasis: A Case Report.
Jibril A, Stevens AC
Am J Case Rep 2018 Feb 13;19:158-162. doi: 10.12659/ajcr.906679. PMID: 29434183Free PMC Article
Immunohistochemical Differentiation of Plasmacytoid Urothelial Carcinoma From Secondary Carcinoma Involvement of the Bladder.
Borhan WM, Cimino-Mathews AM, Montgomery EA, Epstein JI
Am J Surg Pathol 2017 Nov;41(11):1570-1575. doi: 10.1097/PAS.0000000000000922. PMID: 28786878
Metastatic plasmacytoid urothelial carcinoma: a case report and review of the literature.
Olsen DL, Anderson SR
Acta Cytol 2014;58(1):108-12. Epub 2013 Dec 10 doi: 10.1159/000356420. PMID: 24334972
Divergent differentiation in urothelial carcinoma and other bladder cancer subtypes with selected mimics.
Shanks JH, Iczkowski KA
Histopathology 2009 Jun;54(7):885-900. Epub 2008 Oct 30 doi: 10.1111/j.1365-2559.2008.03167.x. PMID: 19178589

Therapy

Carcinoma arising in ileal conduit or orthotopic ileal neobladder reconstruction: A 20-year single institute experience.
Collins K, Yocum BP, Idrees MT, Saeed O
Histopathology 2024 Jul;85(1):182-189. Epub 2024 Apr 2 doi: 10.1111/his.15182. PMID: 38566342
Metastatic Bladder Cancer Expression and Subcellular Localization of Nectin-4 and Trop-2 in Variant Histology: A Rapid Autopsy Study.
Ghali F, Vakar-Lopez F, Roudier MP, Garcia J, Arora S, Cheng HH, Schweizer MT, Haffner MC, Lee JK, Yu EY, Grivas P, Montgomery B, Hsieh AC, Wright JL, Lam HM
Clin Genitourin Cancer 2023 Dec;21(6):669-678. Epub 2023 May 25 doi: 10.1016/j.clgc.2023.05.014. PMID: 37344281Free PMC Article
Metastatic Plasmacytoid Bladder Cancer Harboring a CDH-1 Mutation and Producing High Levels of CA 19-9. A Case Report and Literature Review.
Telfah M, Parikh RA, Zhang D, Kasi A
Am J Case Rep 2020 Jul 9;21:e923130. doi: 10.12659/AJCR.923130. PMID: 32644978Free PMC Article
What Is the Prognostic and Clinical Importance of Urothelial and Nonurothelial Histological Variants of Bladder Cancer in Predicting Oncological Outcomes in Patients with Muscle-invasive and Metastatic Bladder Cancer? A European Association of Urology Muscle Invasive and Metastatic Bladder Cancer Guidelines Panel Systematic Review.
Veskimäe E, Espinos EL, Bruins HM, Yuan Y, Sylvester R, Kamat AM, Shariat SF, Witjes JA, Compérat EM
Eur Urol Oncol 2019 Nov;2(6):625-642. Epub 2019 Oct 8 doi: 10.1016/j.euo.2019.09.003. PMID: 31601522
A Case of Plasmacytoid Variant of Bladder Cancer With a Single Penile Metastasis and a Complete Response to Carboplatin-Based Chemotherapy and Review of the Literature.
Messina C, Zanardi E, Dellepiane C, Tomasello L, Colecchia M, Ravetti GL, Boccardo F, Spina B
Clin Genitourin Cancer 2016 Feb;14(1):e139-42. Epub 2015 Oct 28 doi: 10.1016/j.clgc.2015.10.012. PMID: 26627132

Prognosis

Adjuvant Chemotherapy and Survival After Radical Cystectomy in Histologic Subtype Bladder Cancer.
Koehne EL, Bakaloudi DR, Ghali F, Nyame Y, Schade GR, Grivas P, Yezefski TA, Hawley JE, Yu EY, Hsieh AC, Montgomery RB, Psutka SP, Gore JL, Wright JL
Clin Genitourin Cancer 2024 Jun;22(3):102100. Epub 2024 Apr 25 doi: 10.1016/j.clgc.2024.102100. PMID: 38763862
Plasmacytoid Urothelial Carcinoma of Ureter with Retroperitoneal Metastasis: A Case Report.
Jibril A, Stevens AC
Am J Case Rep 2018 Feb 13;19:158-162. doi: 10.12659/ajcr.906679. PMID: 29434183Free PMC Article
Metastatic plasmacytoid urothelial carcinoma: a case report and review of the literature.
Olsen DL, Anderson SR
Acta Cytol 2014;58(1):108-12. Epub 2013 Dec 10 doi: 10.1159/000356420. PMID: 24334972
Plasmacytoid urothelial carcinoma, a chemosensitive cancer with poor prognosis, and peritoneal carcinomatosis.
Dayyani F, Czerniak BA, Sircar K, Munsell MF, Millikan RE, Dinney CP, Siefker-Radtke AO
J Urol 2013 May;189(5):1656-61. Epub 2012 Nov 15 doi: 10.1016/j.juro.2012.11.084. PMID: 23159581Free PMC Article
Divergent differentiation in urothelial carcinoma and other bladder cancer subtypes with selected mimics.
Shanks JH, Iczkowski KA
Histopathology 2009 Jun;54(7):885-900. Epub 2008 Oct 30 doi: 10.1111/j.1365-2559.2008.03167.x. PMID: 19178589

Clinical prediction guides

What Is the Prognostic and Clinical Importance of Urothelial and Nonurothelial Histological Variants of Bladder Cancer in Predicting Oncological Outcomes in Patients with Muscle-invasive and Metastatic Bladder Cancer? A European Association of Urology Muscle Invasive and Metastatic Bladder Cancer Guidelines Panel Systematic Review.
Veskimäe E, Espinos EL, Bruins HM, Yuan Y, Sylvester R, Kamat AM, Shariat SF, Witjes JA, Compérat EM
Eur Urol Oncol 2019 Nov;2(6):625-642. Epub 2019 Oct 8 doi: 10.1016/j.euo.2019.09.003. PMID: 31601522
Small cell carcinoma of the urinary bladder: a clinicopathological and immunohistochemical analysis of 81 cases.
Wang G, Xiao L, Zhang M, Kamat AM, Siefker-Radtke A, Dinney CP, Czerniak B, Guo CC
Hum Pathol 2018 Sep;79:57-65. Epub 2018 May 12 doi: 10.1016/j.humpath.2018.05.005. PMID: 29763719Free PMC Article
Immunohistochemical Differentiation of Plasmacytoid Urothelial Carcinoma From Secondary Carcinoma Involvement of the Bladder.
Borhan WM, Cimino-Mathews AM, Montgomery EA, Epstein JI
Am J Surg Pathol 2017 Nov;41(11):1570-1575. doi: 10.1097/PAS.0000000000000922. PMID: 28786878
Clinical significance of prominent retraction clefts in invasive urothelial carcinoma.
Shah TS, Kaag M, Raman JD, Chan W, Tran T, Kunchala S, Shuman L, DeGraff DJ, Chen G, Warrick JI
Hum Pathol 2017 Mar;61:90-96. Epub 2016 Nov 4 doi: 10.1016/j.humpath.2016.10.021. PMID: 27818288
Nuclear E-cadherin expression is associated with the loss of membranous E-cadherin, plasmacytoid differentiation and reduced overall survival in urothelial carcinoma of the bladder.
Keck B, Wach S, Kunath F, Bertz S, Taubert H, Lehmann J, Stöckle M, Wullich B, Hartmann A
Ann Surg Oncol 2013 Jul;20(7):2440-5. Epub 2012 Oct 30 doi: 10.1245/s10434-012-2709-4. PMID: 23108554

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...