U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Null Cell Pituitary Neuroendocrine Tumor

MedGen UID:
311062
•Concept ID:
C1709286
•
Neoplastic Process
Synonyms: Hormone Immunonegative Adenoma; Hormone Immunonegative Pituitary Gland Adenoma; Null Cell Adenoma; Null Cell PitNET/Adenoma; Null Cell Pituitary Neuroendocrine Tumor/Adenoma; Transcription Factor-Immunonegative Adenoma

Definition

A non-functioning pituitary neuroendocrine tumor without hormonal immunoreactivity or evidence of specific adenohypophyseal cell derivation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNull Cell Pituitary Neuroendocrine Tumor

Professional guidelines

PubMed

Efficacy and safety of temozolomide in the treatment of aggressive pituitary neuroendocrine tumours in Spain.
Lamas C, Cámara R, Fajardo C, Remon-Ruiz P, Biagetti B, Guerrero-Pérez F, Araujo-Castro M, Mora M, Hanzu F, Iglesias P, García-Centeno R, Soto A
Front Endocrinol (Lausanne) 2023;14:1204206. Epub 2023 Aug 31 doi: 10.3389/fendo.2023.1204206. PMID: 37720528Free PMC Article
Genetic engineering to study testicular tumorigenesis.
Yan W, Burns KH, Matzuk MM
APMIS 2003 Jan;111(1):174-81; discussion 182-3. doi: 10.1034/j.1600-0463.2003.1110121.x. PMID: 12760377
Classical pituitary apoplexy: clinical features, management and outcome.
Randeva HS, Schoebel J, Byrne J, Esiri M, Adams CB, Wass JA
Clin Endocrinol (Oxf) 1999 Aug;51(2):181-8. doi: 10.1046/j.1365-2265.1999.00754.x. PMID: 10468988

Recent clinical studies

Diagnosis

Immunohistochemical and ultrastructural review of six cases previously diagnosed as null cell PitNETs.
Inoshita N, Yoshimoto T, Takazawa Y, Fukuhara N, Okada M, Nishioka H, Yamada S
Brain Tumor Pathol 2023 Jul;40(3):158-162. Epub 2023 Apr 18 doi: 10.1007/s10014-023-00462-9. PMID: 37072666

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...