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Functioning Pituitary Neuroendocrine Tumor/Macroadenoma

MedGen UID:
889109
Concept ID:
C4054917
Neoplastic Process
Synonyms: Functioning PitNET/Macroadenoma; Functioning Pituitary Gland Macroadenoma

Definition

A pituitary neuroendocrine tumor/macroadenoma associated with a hormonal syndrome. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFunctioning Pituitary Neuroendocrine Tumor/Macroadenoma

Professional guidelines

PubMed

Tritos NA, Miller KK
JAMA 2023 Apr 25;329(16):1386-1398. doi: 10.1001/jama.2023.5444. PMID: 37097352
Ershadinia N, Tritos NA
Mayo Clin Proc 2022 Feb;97(2):333-346. doi: 10.1016/j.mayocp.2021.11.007. PMID: 35120696
Chanson P, Raverot G, Castinetti F, Cortet-Rudelli C, Galland F, Salenave S; French Endocrinology Society non-functioning pituitary adenoma work-group
Ann Endocrinol (Paris) 2015 Jul;76(3):239-47. Epub 2015 Jun 10 doi: 10.1016/j.ando.2015.04.002. PMID: 26072284

Recent clinical studies

Etiology

Luger A, Broersen LHA, Biermasz NR, Biller BMK, Buchfelder M, Chanson P, Jorgensen JOL, Kelestimur F, Llahana S, Maiter D, Mintziori G, Petraglia F, Verkauskiene R, Webb SM, Dekkers OM
Eur J Endocrinol 2021 Aug 23;185(3):G1-G33. doi: 10.1530/EJE-21-0462. PMID: 34425558
Muthukumar N
Neurol India 2020 May-Jun;68(Supplement):S72-S78. doi: 10.4103/0028-3886.287669. PMID: 32611895
Chanson P, Raverot G, Castinetti F, Cortet-Rudelli C, Galland F, Salenave S; French Endocrinology Society non-functioning pituitary adenoma work-group
Ann Endocrinol (Paris) 2015 Jul;76(3):239-47. Epub 2015 Jun 10 doi: 10.1016/j.ando.2015.04.002. PMID: 26072284
Lazaro CM, Guo WY, Sami M, Hindmarsh T, Ericson K, Hulting AL, Wersäll J
Neuroradiology 1994;36(2):111-4. doi: 10.1007/BF00588072. PMID: 8183446
Chacko AG, Chandy MJ
Br J Neurosurg 1992;6(3):233-6. doi: 10.3109/02688699209002931. PMID: 1632922

Diagnosis

Tritos NA, Miller KK
JAMA 2023 Apr 25;329(16):1386-1398. doi: 10.1001/jama.2023.5444. PMID: 37097352
Kolitz T, Greenman Y
Pituitary 2023 Jun;26(3):278-280. Epub 2023 Feb 14 doi: 10.1007/s11102-023-01298-4. PMID: 36786972
Luger A, Broersen LHA, Biermasz NR, Biller BMK, Buchfelder M, Chanson P, Jorgensen JOL, Kelestimur F, Llahana S, Maiter D, Mintziori G, Petraglia F, Verkauskiene R, Webb SM, Dekkers OM
Eur J Endocrinol 2021 Aug 23;185(3):G1-G33. doi: 10.1530/EJE-21-0462. PMID: 34425558
Chanson P, Raverot G, Castinetti F, Cortet-Rudelli C, Galland F, Salenave S; French Endocrinology Society non-functioning pituitary adenoma work-group
Ann Endocrinol (Paris) 2015 Jul;76(3):239-47. Epub 2015 Jun 10 doi: 10.1016/j.ando.2015.04.002. PMID: 26072284
Ben-Shlomo A, Melmed S
Endocrinol Metab Clin North Am 2008 Mar;37(1):101-22, viii. doi: 10.1016/j.ecl.2007.10.002. PMID: 18226732Free PMC Article

Therapy

Tritos NA, Miller KK
JAMA 2023 Apr 25;329(16):1386-1398. doi: 10.1001/jama.2023.5444. PMID: 37097352
Kolitz T, Greenman Y
Pituitary 2023 Jun;26(3):278-280. Epub 2023 Feb 14 doi: 10.1007/s11102-023-01298-4. PMID: 36786972
Ershadinia N, Tritos NA
Mayo Clin Proc 2022 Feb;97(2):333-346. doi: 10.1016/j.mayocp.2021.11.007. PMID: 35120696
Ben-Shlomo A, Melmed S
Endocrinol Metab Clin North Am 2008 Mar;37(1):101-22, viii. doi: 10.1016/j.ecl.2007.10.002. PMID: 18226732Free PMC Article
Foroozan R, Bhatti MT, Rhoton AL
Surv Ophthalmol 2004 May-Jun;49(3):349-58. doi: 10.1016/j.survophthal.2004.02.008. PMID: 15110671

Prognosis

Araujo-Castro M, Biagetti B, Menéndez Torre E, Novoa-Testa I, Cordido F, Pascual Corrales E, Rodríguez Berrocal V, Guerrero-Pérez F, Vicente A, Percovich JC, García Centeno R, González L, Ollero García MD, Irigaray Echarri A, Moure Rodríguez MD, Novo-Rodríguez C, Calatayud M, Villar R, Bernabéu I, Alvarez-Escola C, Benítez Valderrama P, Tenorio-Jimenéz C, Abellán Galiana P, Venegas Moreno E, González Molero I, Iglesias P, Blanco C, Vidal-Ostos De Lara F, de Miguel P, López Mezquita E, Hanzu F, Aldecoa I, Lamas C, Aznar S, Aulinas A, Calabrese A, Gracia P, Recio-Córdova JM, Aviles M, Asensio-Wandosel D, Sampedro M, Ruz-Caracuel I, Camara R, Paja M, Fajardo-Montañana C, Marazuela M, Puig-Domingo M
J Clin Endocrinol Metab 2024 Nov 18;109(12):e2178-e2187. doi: 10.1210/clinem/dgae126. PMID: 38436926
Hamblin R, Fountas A, Lithgow K, Loughrey PB, Bonanos E, Shinwari SK, Mitchell K, Shah S, Grixti L, Matheou M, Isand K, McLaren DS, Surya A, Ullah HZ, Klaucane K, Jayasuriya A, Bhatti S, Mavilakandy A, Ahsan M, Mathew S, Hussein Z, Jansz T, Wunna W, MacFarlane J, Ayuk J, Abraham P, Drake WM, Gurnell M, Brooke A, Baldeweg SE, Sam AH, Martin N, Higham C, Reddy N, Levy MJ, Ahluwalia R, Newell-Price J, Vamvakopoulos J, Krishnan A, Lansdown A, Murray RD, Pal A, Bradley K, Mamoojee Y, Purewal T, Panicker J, Freel EM, Hasan F, Kumar M, Jose B, Hunter SJ, Karavitaki N
Eur J Endocrinol 2023 Jul 20;189(1):87-95. doi: 10.1093/ejendo/lvad070. PMID: 37345849
Ershadinia N, Tritos NA
Mayo Clin Proc 2022 Feb;97(2):333-346. doi: 10.1016/j.mayocp.2021.11.007. PMID: 35120696
Lopes MBS
Pituitary 2020 Feb;23(1):3-8. doi: 10.1007/s11102-019-00997-1. PMID: 31641970
Chacko AG, Chandy MJ
Br J Neurosurg 1992;6(3):233-6. doi: 10.3109/02688699209002931. PMID: 1632922

Clinical prediction guides

Rikvold SD, Pedersen MB, Andreassen M, Krogh J
Horm Metab Res 2023 Jul;55(7):443-451. Epub 2023 Jul 10 doi: 10.1055/a-2096-1340. PMID: 37494058
Hamblin R, Fountas A, Lithgow K, Loughrey PB, Bonanos E, Shinwari SK, Mitchell K, Shah S, Grixti L, Matheou M, Isand K, McLaren DS, Surya A, Ullah HZ, Klaucane K, Jayasuriya A, Bhatti S, Mavilakandy A, Ahsan M, Mathew S, Hussein Z, Jansz T, Wunna W, MacFarlane J, Ayuk J, Abraham P, Drake WM, Gurnell M, Brooke A, Baldeweg SE, Sam AH, Martin N, Higham C, Reddy N, Levy MJ, Ahluwalia R, Newell-Price J, Vamvakopoulos J, Krishnan A, Lansdown A, Murray RD, Pal A, Bradley K, Mamoojee Y, Purewal T, Panicker J, Freel EM, Hasan F, Kumar M, Jose B, Hunter SJ, Karavitaki N
Eur J Endocrinol 2023 Jul 20;189(1):87-95. doi: 10.1093/ejendo/lvad070. PMID: 37345849
Tritos NA, Miller KK
JAMA 2023 Apr 25;329(16):1386-1398. doi: 10.1001/jama.2023.5444. PMID: 37097352
Ershadinia N, Tritos NA
Mayo Clin Proc 2022 Feb;97(2):333-346. doi: 10.1016/j.mayocp.2021.11.007. PMID: 35120696
Molitch ME
J Clin Endocrinol Metab 1995 Jan;80(1):3-6. doi: 10.1210/jcem.80.1.7829630. PMID: 7829630

Recent systematic reviews

Kajal S, Ahmad YES, Halawi A, Gol MAK, Ashley W
Pituitary 2024 Aug;27(4):320-334. Epub 2024 Jun 27 doi: 10.1007/s11102-024-01412-0. PMID: 38935252
Rikvold SD, Pedersen MB, Andreassen M, Krogh J
Horm Metab Res 2023 Jul;55(7):443-451. Epub 2023 Jul 10 doi: 10.1055/a-2096-1340. PMID: 37494058
Pelsma ICM, Verstegen MJT, de Vries F, Notting IC, Broekman MLD, van Furth WR, Biermasz NR, Pereira AM
Pituitary 2020 Aug;23(4):417-429. doi: 10.1007/s11102-020-01044-0. PMID: 32419072Free PMC Article
Cossu G, Daniel RT, Pierzchala K, Berhouma M, Pitteloud N, Lamine F, Colao A, Messerer M
Pituitary 2019 Feb;22(1):79-88. doi: 10.1007/s11102-018-0921-3. PMID: 30390277
Wen G, Tang C, Zhong C, Li X, Li J, Li L, Yang Y, Ma C
PLoS One 2016;11(4):e0153397. Epub 2016 Apr 28 doi: 10.1371/journal.pone.0153397. PMID: 27124276Free PMC Article

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