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Abnormal immune system morphology

MedGen UID:
1702861
•Concept ID:
C5139223
•
Pathologic Function
HPO: HP:0032251

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal immune system morphology

Professional guidelines

PubMed

POEMS syndrome: 2021 Update on diagnosis, risk-stratification, and management.
Dispenzieri A
Am J Hematol 2021 Jul 1;96(7):872-888. Epub 2021 May 31 doi: 10.1002/ajh.26240. PMID: 34000085
Systemic mastocytosis in adults: 2021 Update on diagnosis, risk stratification and management.
Pardanani A
Am J Hematol 2021 Apr 1;96(4):508-525. Epub 2021 Feb 21 doi: 10.1002/ajh.26118. PMID: 33524167
Hemolytic Anemia: Evaluation and Differential Diagnosis.
Phillips J, Henderson AC
Am Fam Physician 2018 Sep 15;98(6):354-361. PMID: 30215915

Recent clinical studies

Etiology

Primary and secondary defects of the thymus.
Dinges SS, Amini K, Notarangelo LD, Delmonte OM
Immunol Rev 2024 Mar;322(1):178-211. Epub 2024 Jan 16 doi: 10.1111/imr.13306. PMID: 38228406Free PMC Article
Gastrointestinal involvement in Klippel-Trénaunay syndrome: pathophysiology, evaluation, and management.
Wang H, Lin W, Xie C, Yang W, Zhou J, Guo Z
Orphanet J Rare Dis 2023 Sep 12;18(1):288. doi: 10.1186/s13023-023-02857-5. PMID: 37700367Free PMC Article
Kabuki syndrome: review of the clinical features, diagnosis and epigenetic mechanisms.
Wang YR, Xu NX, Wang J, Wang XM
World J Pediatr 2019 Dec;15(6):528-535. Epub 2019 Oct 5 doi: 10.1007/s12519-019-00309-4. PMID: 31587141
Vascular malformations.
Arneja JS, Gosain AK
Plast Reconstr Surg 2008 Apr;121(4):195e-206e. doi: 10.1097/01.prs.0000304607.29622.3c. PMID: 18349599
Splenogonadal fusion.
Balaji KC, Caldamone AA, Rabinowitz R, Ortenberg J, Diamond DA
J Urol 1996 Aug;156(2 Pt 2):854-6. doi: 10.1097/00005392-199608001-00086. PMID: 8683800

Diagnosis

Congenital Vascular and Lymphatic Diseases.
Jung R, Trivedi CM
Circ Res 2024 Jun 21;135(1):159-173. Epub 2024 Jun 20 doi: 10.1161/CIRCRESAHA.124.323181. PMID: 38900856Free PMC Article
Immunodeficiency in CHARGE syndrome.
Mehr S, Hsu P, Campbell D
Am J Med Genet C Semin Med Genet 2017 Dec;175(4):516-523. Epub 2017 Nov 21 doi: 10.1002/ajmg.c.31594. PMID: 29159871
Plastic Bronchitis.
Rubin BK
Clin Chest Med 2016 Sep;37(3):405-8. Epub 2016 Jun 15 doi: 10.1016/j.ccm.2016.04.003. PMID: 27514587
The thymus gland.
Askin DF, Young S
Neonatal Netw 2001 Dec;20(8):7-13. doi: 10.1891/0730-0832.20.8.7. PMID: 12144107
Noonan syndrome.
Allanson JE
J Med Genet 1987 Jan;24(1):9-13. doi: 10.1136/jmg.24.1.9. PMID: 3543368Free PMC Article

Therapy

Immunotherapy: A promising novel endometriosis therapy.
Li W, Lin A, Qi L, Lv X, Yan S, Xue J, Mu N
Front Immunol 2023;14:1128301. Epub 2023 Apr 17 doi: 10.3389/fimmu.2023.1128301. PMID: 37138868Free PMC Article
NK cell-based cancer immunotherapy: from basic biology to clinical development.
Liu S, Galat V, Galat Y, Lee YKA, Wainwright D, Wu J
J Hematol Oncol 2021 Jan 6;14(1):7. doi: 10.1186/s13045-020-01014-w. PMID: 33407739Free PMC Article
Plastic Bronchitis.
Rubin BK
Clin Chest Med 2016 Sep;37(3):405-8. Epub 2016 Jun 15 doi: 10.1016/j.ccm.2016.04.003. PMID: 27514587
Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Inclusion body myositis.
Tawil R, Griggs RC
Curr Opin Rheumatol 2002 Nov;14(6):653-7. doi: 10.1097/00002281-200211000-00004. PMID: 12410086

Prognosis

Pearls and Pitfalls in Imaging Bone Marrow in Pediatric Patients.
Patel MD, Brian J, Chauvin NA
Semin Ultrasound CT MR 2020 Oct;41(5):472-487. Epub 2020 May 28 doi: 10.1053/j.sult.2020.05.012. PMID: 32980094
The bicuspid aortic valve: Is it an immunological disease process?
Howard C, Picca L, Smith T, Sharif M, Bashir M, Harky A
J Card Surg 2019 Jun;34(6):482-494. Epub 2019 Apr 23 doi: 10.1111/jocs.14050. PMID: 31012137
Percutaneous Treatment of Lymphatic Malformations.
Acord M, Srinivasan AS, Cahill AM
Tech Vasc Interv Radiol 2016 Dec;19(4):305-311. Epub 2016 Oct 6 doi: 10.1053/j.tvir.2016.10.001. PMID: 27993327
Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Biliary atresia: clinical aspects.
Davenport M
Semin Pediatr Surg 2012 Aug;21(3):175-84. doi: 10.1053/j.sempedsurg.2012.05.010. PMID: 22800970

Clinical prediction guides

Pearls and Pitfalls in Imaging Bone Marrow in Pediatric Patients.
Patel MD, Brian J, Chauvin NA
Semin Ultrasound CT MR 2020 Oct;41(5):472-487. Epub 2020 May 28 doi: 10.1053/j.sult.2020.05.012. PMID: 32980094
Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging.
Ma S, Sun S, Geng L, Song M, Wang W, Ye Y, Ji Q, Zou Z, Wang S, He X, Li W, Esteban CR, Long X, Guo G, Chan P, Zhou Q, Belmonte JCI, Zhang W, Qu J, Liu GH
Cell 2020 Mar 5;180(5):984-1001.e22. Epub 2020 Feb 27 doi: 10.1016/j.cell.2020.02.008. PMID: 32109414
Percutaneous Treatment of Lymphatic Malformations.
Acord M, Srinivasan AS, Cahill AM
Tech Vasc Interv Radiol 2016 Dec;19(4):305-311. Epub 2016 Oct 6 doi: 10.1053/j.tvir.2016.10.001. PMID: 27993327
Autoantibodies in autism spectrum disorders (ASD).
Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral D, Van de Water J
Ann N Y Acad Sci 2007 Jun;1107:79-91. doi: 10.1196/annals.1381.009. PMID: 17804535
Developmental disorders of the lymphatic system.
Greenlee R, Hoyme H, Witte M, Crowe P, Witte C
Lymphology 1993 Dec;26(4):156-68. PMID: 8121193

Recent systematic reviews

The 2021 European Alliance of Associations for Rheumatology/American College of Rheumatology points to consider for diagnosis and management of autoinflammatory type I interferonopathies: CANDLE/PRAAS, SAVI and AGS.
Cetin Gedik K, Lamot L, Romano M, Demirkaya E, Piskin D, Torreggiani S, Adang LA, Armangue T, Barchus K, Cordova DR, Crow YJ, Dale RC, Durrant KL, Eleftheriou D, Fazzi EM, Gattorno M, Gavazzi F, Hanson EP, Lee-Kirsch MA, Montealegre Sanchez GA, Neven B, Orcesi S, Ozen S, Poli MC, Schumacher E, Tonduti D, Uss K, Aletaha D, Feldman BM, Vanderver A, Brogan PA, Goldbach-Mansky R
Ann Rheum Dis 2022 May;81(5):601-613. Epub 2022 Jan 27 doi: 10.1136/annrheumdis-2021-221814. PMID: 35086813Free PMC Article
Tumefactive Virchow-Robin spaces.
Kwee RM, Kwee TC
Eur J Radiol 2019 Feb;111:21-33. Epub 2018 Dec 13 doi: 10.1016/j.ejrad.2018.12.011. PMID: 30691661
Epidermoid cyst in intrapancreatic accessory spleen: A systematic review.
Li BQ, Lu J, Seery S, Guo JC
Pancreatology 2019 Jan;19(1):10-16. Epub 2018 Oct 22 doi: 10.1016/j.pan.2018.10.008. PMID: 30366677
Prevalence of adenoid hypertrophy: A systematic review and meta-analysis.
Pereira L, Monyror J, Almeida FT, Almeida FR, Guerra E, Flores-Mir C, Pachêco-Pereira C
Sleep Med Rev 2018 Apr;38:101-112. Epub 2017 Jun 14 doi: 10.1016/j.smrv.2017.06.001. PMID: 29153763
The prevalence and morphometry of an accessory spleen: A meta-analysis and systematic review of 22,487 patients.
Vikse J, Sanna B, Henry BM, Taterra D, Sanna S, Pękala PA, Walocha JA, Tomaszewski KA
Int J Surg 2017 Sep;45:18-28. Epub 2017 Jul 15 doi: 10.1016/j.ijsu.2017.07.045. PMID: 28716661

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